Incorrect structure proposal for delta-aminolevulinic acid derivative
نویسندگان
چکیده
منابع مشابه
Bone marrow delta-aminolevulinic acid synthetase activity in hematological disorders.
An improved radiochemical method to measure the o-aminoJevulinic acid (ALA) synthetase activity in human bone marrow erythroblasts by incubating bone marrow cell homogenate with 14C-succinate and succinyl CoA generating system has been reported. Studies were made to obtain the optimal conditions for the enzyme assay and to confirm the reliability of the assay procedures. ALA-synthetase in eryth...
متن کاملPrenatal lead exposure, delta-aminolevulinic acid, and schizophrenia.
Schizophrenia is a severe mental disorder of unknown etiology. Recent reports suggest that a number of environmental factors during prenatal development may be associated with schizophrenia. We tested the hypothesis that environmental lead exposure may be associated with schizophrenia using archived serum samples from a cohort of live births enrolled between 1959 and 1966 in Oakland, California...
متن کاملOptimized fluorometric determination of urinary delta-aminolevulinic acid by using pre-column derivatization, and identification of the derivative.
We previously reported the usefulness of a fluorometric method to determine urinary delta-aminolevulinic acid (ALA) concentrations by using post-column derivatization to monitor the effect of lead exposure. We have further improved the method by introducing pre-column derivatization by using reaction of ALA with acetylacetone and formaldehyde. Response of the hematopoietic system to lead exposu...
متن کاملDelta-aminolevulinic acid dehydratase (ALAD) polymorphism in lead exposed Bangladeshi children and its effect on urinary aminolevulinic acid (ALA).
BACKGROUND AND OBJECTIVE Lead has long been recognized as a harmful environmental pollutant. People in developing countries like Bangladesh still have a higher risk of lead exposure. Previous research has suggested that the delta-aminolevulinic acid dehydratase (ALAD) genotype can modify lead toxicity and individual susceptibility. As children are more susceptible to lead-induced toxicity, this...
متن کاملControl of hemoglobin synthesis in the cultured chick blastoderm by delta-aminolevulinic acid synthetase: increase in the rate of hemoglobin formation with delta-aminolevulinic acid.
The early, de-embryonated chick blastoderm, cultured in vitro, closely simulates a phased culture of erythroid cells. This fact permits the study of hemoglobin synthesis from colorless erythroblast precursor cells to fully hemoglobinated erythrocytes. When b-aminolevulinic acid is added to colorless blastoderms, thereby by-passing &aminolevulinic acid synthetase, copious amounts of porphyrins, ...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1991
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/37.6.1135